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The Colts vs Chiefs prediction for this NFL showdown on November 23rd, 2025 provides key betting insights, including AI-driven picks, betting trends, and best odds. With both teams vying for a critical win, bettors are analyzing the Colts vs Chiefs NFL AI Predictions, Consensus Picks, Best Odds player props, consensus picks and public betting trends to find the best value plays.
Preview
This NFL matchup between Colts vs Chiefs is drawing attention from bettors searching for value plays. While sportsbooks may list the Chiefs as the favorite, recent performances suggest this could be a closer contest than expected.
Who is Favored to Win?
Opening Line:
- Colts: -154 (FanDuel)
- Chiefs: -170 (DraftKings)
The Colts vs Chiefs odds positions the Chiefs as a significant favorite, with sportsbooks expecting a high-scoring contest.
Betting History for Colts vs Chiefs
This game has featured high-scoring affairs and strong performances from Colts vs Chiefs.
Moneyline Betting History
Below is the moneyline history for the Colts vs Chiefs matchup. The Colts have won 5 out of their last 6 games outright while the Chiefs have won 3 out out of their last 6 games.
Colts Moneyline
History
Chiefs Moneyline
History
Spread Betting History
Below is the spread history for the Colts vs Chiefs pick. The Colts have covered the spread in 3 out of their last 6 games while the Chiefs have covered in 3 of the last 5 games.
Colts Spread
History
Chiefs Spread
History
Total Betting History
Below is the total history for the Colts vs Chiefs pick. The total for the Colts has gone over 4 times of their last 6 games while the total for the Chiefs hasn’t gone over at all in the last 5 games.
Colts Total
History
Chiefs Total
History
Consensus Picks for Colts vs Chiefs
Public betting trends provide insight into Colts vs Chiefs consensus picks, helping bettors identify where the sharp and public money is heading.
Moneyline, Spread, and Total Trends
Check out the images below for the Colts vs Chiefs NFL public betting trends. Majority of the money is on the Chiefs for the moneyline and the spread while there is a heavy amount of money on the under.
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Spread
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Over/Under
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SharpMush™ Data for Colts vs Chiefs
SharpMush™ highlights the difference in betting behavior between sharp (high-performing) and mush (low-performing) bettors. It shows where sharp bettors are siding more heavily than bad bettors, helping users identify betting angles with potential value—or traps to avoid.
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SharpMush
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Prediction for Colts vs Chiefs for NFL
Our advanced AI betting algorithms have analyzed the data, trends, and betting splits to bring you the best Colts vs Chiefs pick from our AI sports betting bot.
We have an NFL AI betting bot that give you NFL AI sports predictions for every Sunday.
Today’s AI Sports Pick: Colts +3.5
Chip Bayless
A multi-sport specialist who has been known to do it all at the highest level.
45 Day Rankings
Here is where Chip Bayless stands in ranking in comparison to the rest of the Juice Reel betting community.
45 Day Performance
Chip Bayless' record over the past 45 days.
Expert Picks and Predictions for Colts vs Chiefs
Our expert sports bettors have their picks in for the Colts vs Chiefs game.
airtight_sake is betting on the Colts +3.5 while IkelsFly is also betting on the Chiefs to be winning after 1 quarter.
There are a multitude of ways to take advantage of our handicapper service. You can find the best NFL Handicappers and dominate throughout the entire NFL season. You can also win with the best and make it easy to discover the best handicappers on the app.
If you’re interested in selling sports picks yourself, no better place to start then Juice Reel as you let your record do the marketing for you.
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Best Odds for Colts vs Chiefs Bet Predictions
Finding the Colts vs Chiefs best odds ensures bettors maximize value.
Get the best odds for the under with BetMGM as they are offering under 50.5 and over 49.5 with BetRivers.
Help yourself throughout the NFL season and find the best NFL odds across 300+ sportsbooks.
Lets take a look at how the best odds compare across the top sportsbooks for each type of bet. There’s no better way to keep track of your bets with our sports betting tracker.
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Player Props Bets for Colts vs Chiefs
Finding the Colts vs Chiefs player prop predictions ensures bettors maximize value. It’s important to take advantage of all that Juice Reel has to offer with our player prop predictions.
Take it to the next level and find NFL player prop predictions for all of our NFL games. Beat the books every Monday, Thursday, and Sunday and tail the hottest players.
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Jonathan Taylor Rushing Long – Colts vs Chiefs PrizePicks
The Jonathan Taylor longest rush prop has tons of value with his over/under at 17.5 while he averages 35.5 longest yard rush throughout the season.
- Season Avg: 35.5
- Best Odds: -118
- Pick: Over
Rashee Rice Touchdowns – Colts vs Chiefs PrizePicks
The Rashee Rice touchdowns prop has tons of value with his over/under at 0.5 while he averages 1 touchdown per game throughout the season.
- Season Avg: 1.00
- Best Odds: +110
- Pick: Over
Rashee Rice Receiving Touchdowns – Colts vs Chiefs PrizePicks
The Rashee Rice receiving touchdowns prop has tons of value with his over/under at 0.5 while he averages 0.80 yards throughout the season.
- Season Avg: 0.80
- Best Odds: +110
- Pick: Over
