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The Indiana vs Ohio State prediction for this NCAAF showdown on December 6th, 2025 provides key betting insights, including AI-driven picks, betting trends, and best odds. With both teams vying for a critical win, bettors are analyzing the Indiana vs Ohio State player props, prizepicks, consensus picks, and public betting trends to find the best value plays.
Preview for Indiana vs Ohio State Prediction
This CFB matchup between Indiana vs Ohio State is drawing attention from bettors searching for value plays. While sportsbooks may list Ohio State as the favorite, recent performances suggest this could be a closer contest than expected.
Who is Favored to Win?
Opening Line:
- Indiana: +166 (FanDuel)
- Ohio State: -190 (theScore)
The Indiana vs Ohio State odds positions Ohio State as a significant favorite, with sportsbooks expecting a high-scoring contest.
Betting History for Indiana vs Ohio State
This game has featured high-scoring affairs and strong performances from Indiana vs Ohio State.
Moneyline Betting History for Indiana vs Ohio State
Below is the moneyline history for the Indiana vs Ohio State matchup. The Indiana Hoosiers have won 6 out of their last 6 games outright while the Ohio State Buckeyes have also won 6 of their last 6 games.
Indiana Moneyline
History
Ohio State Moneyline
History
Spread Betting History for Indiana vs Ohio State
Below is the spread history for the Indiana vs Ohio State pick. The Hoosiers have covered the spread in 3 out of their last 6 games while Ohio State has also covered in 5 of the last 6 games.
Indiana Spread
History
Ohio State Spread
History
Total Betting History for Indiana vs Ohio State
Below is the total history for the Indiana vs Ohio State. The total for Indiana has gone over in 3 of their last 6 games while the total for Ohio State has gone over for 5 out of the last 6 games.
Indiana Total
History
Ohio State Total
History
Consensus Picks & Public Betting Trends for Indiana vs Ohio State
Public betting trends provide insight into Indiana vs Ohio State consensus picks, helping bettors identify where the sharp and public money is heading.
Moneyline, Spread, and Total Trends for Indiana vs Ohio State
Check out the images below for the Indiana vs Ohio State public betting trends. Majority of the money is on the Ohio State for the moneyline and the spread while there is a heavy amount of money on the over.
Moneyline
Trends
Spread
Trends
Over/Under
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SharpMush™ Data for Indiana vs Ohio State
SharpMush™ highlights the difference in betting behavior between sharp (high-performing) and mush (low-performing) bettors. It shows where sharp bettors are siding more heavily than bad bettors, helping users identify betting angles with potential value—or traps to avoid.
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SharpMush
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SharpMush
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SharpMush
Prediction for Indiana vs Ohio State for NCAAF
Our advanced AI betting algorithms have analyzed the data, trends, and betting splits to bring you the best Indiana vs Ohio State pick from our AI sports betting bot.
We have a College Football AI betting bot that give you CFB AI sports predictions for every Saturday.
Today’s AI Sports Pick: Ohio State -4.0

Chip Bayless
A multi-sport specialist who has been known to do it all at the highest level.

45 Day Rankings
Here is where Chip Bayless stands in ranking in comparison to the rest of the Juice Reel betting community.

45 Day Performance
Chip Bayless' record over the past 45 days.
Best Odds for Indiana vs Ohio State Bet Predictions
Finding the Indiana vs Ohio State best odds ensures bettors maximize value.
Lets take a look at how the best odds compare across the top sportsbooks for each type of bet. There’s no better way to keep track of your bets with our sports betting tracker.
Moneyline
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Spread
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Over/Under
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Player Props and PrizePicks for Indiana vs Ohio State Bet Predictions
Finding the Indiana vs Ohio State player prop predictions ensures bettors maximize value. It’s important to take advantage of all that Juice Reel has to offer with our player prop predictions.
Take it to the next level and find College Football player prop predictions for all of our CFB games. Beat the books every Thursday, Friday, and Saturday and tail the hottest players.
Want to win even more? Try out our AI Parlay Generator and double and triple your payday.
Beyond our Indiana vs Ohio State AI Predictions and Player Props
Now that you’ve got the best Predictions, Consensus Picks, and Best Odds for the Indiana vs Ohio State, would you like more insights to help you bet smarter?
Juice Reel has a multitude of features like discussed in this article to help you win. Download the AI sports betting app for FREE today and lets beat the books together.


