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The LSU vs Vanderbilt prediction for this NCAAF showdown on October 18th, 2025 provides key betting insights, including AI-driven picks, betting trends, and best odds. With both teams vying for a critical win, bettors are analyzing the LSU vs Vanderbilt player props, prizepicks, consensus picks, and public betting trends to find the best value plays.
Preview for LSU vs Vanderbilt Prediction
This CFB matchup between LSU vs Vanderbilt is drawing attention from bettors searching for value plays. While sportsbooks may list Oregon as the favorite, recent performances suggest this could be a closer contest than expected.
Who is Favored to Win?
Opening Line:
- LSU: +115 (Caesars)
- Vanderbilt: -130 (DraftKings)
The LSU vs Vanderbilt odds positions Vanderbilt as a significant favorite, with sportsbooks expecting a high-scoring contest.
Betting History for LSU vs Vanderbilt
This game has featured high-scoring affairs and strong performances from LSU vs Vanderbilt.
Moneyline Betting History for LSU vs Vanderbilt
Below is the moneyline history for the LSU vs Vanderbilt matchup. The LSU Tigers have won 5 out of their last 6 games outright while Vanderbilt have won 5 of their last 6 games.
LSU Moneyline
History

Vanderbilt Moneyline
History

Spread Betting History for LSU vs Vanderbilt
Below is the spread history for the LSU vs Vanderbilt pick. The LSU Tigers have covered the spread in 3 out of their last 6 games while Vanderbilt have covered in 4 of the last 6 games.
LSU Spread
History

Vanderbilt Spread
History

Total Betting History for LSU vs Vanderbilt
Below is the total history for the LSU vs Vanderbilt. The total for LSU has gone over once of their last 6 games while the total for Vanderbilt has gone over for 3 out of the last 6 games.
LSU Total
History

Vanderbilt Total
History

Consensus Picks & Public Betting Trends for LSU vs Vanderbilt
Public betting trends provide insight into LSU vs Vanderbilt consensus picks, helping bettors identify where the sharp and public money is heading.
Moneyline, Spread, and Total Trends for LSU vs Vanderbilt
Check out the images below for the LSU vs Vanderbilt public betting trends. Majority of the money is on the Vanderbilt for the moneyline and the spread while there is a heavy amount of money on the over.
Moneyline
Trends

Spread
Trends

Over/Under
Trends

SharpMush™ Data for LSU vs Vanderbilt
SharpMush™ highlights the difference in betting behavior between sharp (high-performing) and mush (low-performing) bettors. It shows where sharp bettors are siding more heavily than bad bettors, helping users identify betting angles with potential value—or traps to avoid.
Moneyline
SharpMush

Spread
SharpMush

Over/Under
SharpMush

Prediction for LSU vs Vanderbilt for NCAAF
Our advanced AI betting algorithms have analyzed the data, trends, and betting splits to bring you the best LSU vs Vanderbilt pick from our AI sports betting bot.
We have an College Football AI betting bot that give you CFB AI sports predictions for every Saturday.
Today’s AI Sports Pick: LSU +2.5

Chip Bayless
A multi-sport specialist who has been known to do it all at the highest level.

45 Day Rankings
Here is where Chip Bayless stands in ranking in comparison to the rest of the Juice Reel betting community.

45 Day Performance
Chip Bayless' record over the past 45 days.
Best Odds for LSU vs Vanderbilt Bet Predictions
Finding the LSU vs Vanderbilt best odds ensures bettors maximize value.
Lets take a look at how the best odds compare across the top sportsbooks for each type of bet. There’s no better way to keep track of your bets with our sports betting tracker.

Moneyline
Odds

Spread
Odds

 Over/Under
Odds

Player Props and PrizePicks for LSU vs Vanderbilt Bet Predictions
Finding the LSU vs Vanderbilt player prop predictions ensures bettors maximize value. It’s important to take advantage of all that Juice Reel has to offer with our player prop predictions.
Take it to the next level and find College Football player prop predictions for all of our CFB games. Beat the books every Thursday, Friday, and Saturday and tail the hottest players.
Want to win even more? Try out our AI Parlay Generator and double and triple your payday.
Beyond our LSU vs Vanderbilt AI Predictions and Player Props
Now that you’ve got the best Predictions, Consensus Picks, and Best Odds for the LSU vs Vanderbilt, would you like more insights to help you bet smarter?
Juice Reel has a multitude of features like discussed in this article to help you win. Download the AI sports betting app for FREE today and lets beat the books together.